梅余霞   中共党员  博士   副教授   硕士生导师  

教育经历

2011年获华中农业大学生命科学技术学院微生物学专业理学博士学位

科研与学术工作经历

2017-2018 美国加州大学戴维斯分校访问学者

2002-至今 华中农业大学生命科学技术学院 助教，讲师，副教授

研究方向

主要致力于应用微生物与生物工程领域的研究，研究方向包括：微生物资源利用，功能糖在农业、食品等行业的应用开发，真菌主要活性物质的合成代谢调控（基于合成途径的基因调控分析、菌株选育与发酵工艺优化）以及生物学功能的作用机制研究（从作用靶点、信号传导途径、肠道菌群调节等角度分析抗肿瘤、抗炎、增强机体免疫力等功能的机制）

代表性研究成果

论文

1.    Zhang YT, Li DY, Wang Z, Zang WT, Rao P, Liang YX, Mei YX*, Alpha-terpineol affects synthesis and antitumor activity of triterpenoids from Antrodia cinnamomea mycelia in solid-state culture, Food & Function, 2018, 9(12): 6517~6525

2.    Zhang YT, Wang Z, Li DY, Zang WT, Zhu H, Wu PY, Mei YX*, Liang YX*, A polysaccharide from Antrodia cinnamomea mycelia exerts antitumor activity through blocking of TOP1/TDP1-mediated DNA repair pathway, International Journal of Biological Macromolecules, 2018, 120(PtB): 1551~1560

3.    Li YL, Chen L, Liu YY, Zhang Y, Liang YX, Mei YX*, Anti-inflammatory effects in a mouse osteoarthritis model of a mixture of glucosamine and chitooligosaccharides produced by bi-enzyme single-step hydrolysis, Scientific Reports, 2018.4.4, 8(1): 5624

4.    Wang YG, Li B, Zhang XD, Peng N, Mei YX*, Liang YX*, Low molecular weight chitosan is an effective antifungal agent against Botryosphaeria sp. and preservative agent for pear (Pyrus) fruits, International Journal of Biological Macromolecules, 2016.11.3, 95: 1135~1143

5.    Liu YY, Wang CR, Li JS, Mei YX, Liang YX*, Hypoglycemic and hypolipidemic effects of Phellinus Linteus mycelial extract from solid-state culture in a rat model of type 2 diabetes, Nutrients, 2019.1.30, 11(2): 296

6.    Mei YX, Dai XY, Yang W, Xu XW, & Liang YX. Antifungal activity of chitooligosaccharides against the dermatophyte Trichophyton rubrum. International Journal of Biological Macromolecules, 2015, 77: 330-335.

7.    Mei YX, Zhu H, Hu QM, Liu YY, Zhao SM, Peng N & Liang YX*. A novel polysaccharide from mycelia of cultured Phellinus linteus displays antitumor activity through apoptosis. Carbohydrate Polymers, 2015, 124: 90-97.

8.    Mei YX, Yang W, Zhu, PX, Peng N, Zhu H, & Liang YX*. Isolation, characterization, and antitumor activity of a novel heteroglycan from cultured mycelia of Cordyceps sinensis. Planta Medica, 2014, 80(13): 1107-1112.

9.    Mei YX, Chen HX, Zhang J, Zhang XD, Liang YX*. Protective effect of chitooligosaccharides against cyclophosphamide-induced immunosuppression in mice. International Journal of Biological Macromolecules, 2013, 62:330-335.

10.  Mei YX, Peng N, Zhao S, Hu Y, Wang H, Liang Y*, She Q*. Exceptional thermal stability and organic solvent tolerance of an esterase expressed from a thermophilic host. Applied Microbiology and Biotechnology, 2012, 93(5):1965-74.

11.  Hu JL, Lin YX, Zhang Z, Xiang T, Mei, YX, Zhao SM, Liang YX & Peng N*. High-titer lactic acid production by Lactobacillus pentosus FL0421 from corn stover using fed-batch simultaneous saccharification and fermentation. Bioresource Technology, 2016, 214:74-80.

12.  Hu J, Zhang Z, Lin Y, Zhao SM, Mei YX, Liang YX, & Peng N*. High-titer lactic acid production from NaOH-pretreated corn stover by Bacillus coagulans LA204 using fed-batch simultaneous saccharification and fermentation under non-sterile condition. Bioresource Technology, 2015,182: 251-257.

13.  Hu Y, Peng N, Han W, Mei YX, Chen Z, Feng X, Liang YX*, She Q*. An archaeal proteinevolutionarily conserved in prokaryotes is a zinc-dependent metalloprotease. Bioscience Reports, 2012, 32(6):609-18.

14.  Peng N, Deng L, Mei YX, Jiang D, Hu Y, Awayez M, Liang Y, She Q*. A synthetic arabinose-inducible promoter confers high levels of recombinant protein expression in hyperthermophilic archaeon Sulfolobus islandicus. Applied Environmental Microbiology, 2012, 78(16).5630-5637.

15.  Zhu PX, Mei YX, Liang YX, Immunological activity of a purified polysaccharide from Cordyceps Sinensis in vitro, Food Science and Technology, 2013, 38 (9): 25-28. (In Chinese)

16.  Hu QM, Mei YX, Liang YX. Immune activities of polysaccharides isolated in vitro purified from Phellinus linteus, Food Science and Technology, 2013, 38 (9): 142-145. (In Chinese)

17.  Mei YX, Fang BS. Crystallization of xylitol based on fermentation [J]. Food science and technology, 2008, (10):82-85.(In Chinese)

18.  Mei YX, Fang BS. Crystallization kinetics of xylitol based on the broth model [J].Biomass Chemical Engineering, 2007, 41(5):1-4.(In Chinese)

19.  Mei YX, Fang BS. Crystallization thermodynamics of xylitol from fermentation broth [J]. chemistry & bioengineering, 2007, 24(5):45-47.(In Chinese)

其它成果

获科技成果鉴定5项，发明专利7项。

获奖情况

曾获湖北省科技进步三等奖，并多次获得华中农业大学教育质量二等奖、三等奖及青年老师讲课竞赛优胜奖。

主讲课程

生物分离工程、生物工程综合大实验（四）、免疫学、发酵工程与人类生活

研究生招生专业

微生物学、生物工程

联系方式

实验室电话：027-87281040

电子邮箱：mei@mail.hzau.edu.cn

办公地点：微生物农药国家工程研究中心214