生物化学教研室Brief Introduction

 !E arfix">
殷平
时间:2015-11-04

 

殷平 华中农业大学 生命科学技术学院 教授 

受教育经历

2006/09-2009/06   武汉大学,生命科学学院生物化学系,博士 

2003/09-2006/06   武汉大学,生命科学学院生物化学系,硕士 

1999/09-2003/06   武汉大学,生命科学学院生物技术系,学士 

 

研究工作经历

2013.09− Present  Professor

School of Life Sciences and Technology, National key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, Wuhan, P. R. China.

 

Research Interests: 1) Structural and functional study of Pentatricopeptide repeat (PPR) protein;

        2) Structural and biochemical investigation of plant organelle biogenesis.

 

2009.07− 2013.08  Postdoctoral Fellow

         Center of Structural Biology, School of Life Sciences, Tsinghua University, Beijing, P. R. China.

Advisor: Dr Nieng Yan, Professor.

 

Research Interests: 1) Structural and functional study of Pentatricopeptide repeat (PPR) protein;

        2) Investigation of transcription activator-like effectors (TALE);

        3) Structural and functional study of Abscisic acid (ABA) receptor;

 

 

Publications:

2016

Zhang D#, Liu Y#, Wang Q, Guan Z, Wang J, Liu J, Zou T, Yin P*. Structural basis of prokaryotic NAD-RNA decapping by NudC. Cell Research. 2016 Sep;26(9):1062-6. doi: 10.1038/cr.2016.98. Epub 2016 Aug 26.

 

Wang X#, Feng J#, Xue Y#, Guan Z, Zhang D, Liu Z, Gong Z, Wang Q, Huang J, Tang C, Zou T, Yin P*. Structural basis of N6-adenosine methylation by the METTL3-METTL14 complex. Nature. 2016 May 25. doi: 10.1038/nature18298.

 

Shen C#, Zhang D#, Guan Z#, Liu Y, Yang Z, Yang Y, Wang X, Wang Q, Zhang Q, Fan S, Zou T, Yin P*. Structural basis for the specific single-stranded RNA recognition by designer pentatricopeptide repeat protein. Nat. Commun. 2016 Apr 18;7:11285. doi:  10.1038/ncomms11285.

 

2015

Shen C#, Wang X#, Liu Y, Li Q, Yang Z, Yan N, Zou T, Yin P*. Specific RNA recognition by designer pentatricopeptide repeat protein. Mol Plant. 2015 Apr;8(4):667-70.

 

2014

Li Q, Yan C, Xu H, Wang Z, Long J, Li W, Wu J, Yin P*, Yan N*. Examination of the dimerization states of the single-stranded RNA-recognition protein PPR10. J Biol Chem. 2014 Nov 7; 289 (45):31503-12.

 He Y, Hao Q, Li W, Yan C, Yan N*, Yin P*. Identification and characterization of ABA receptors in Oryza sativa. PloS ONE. 2014 Apr 17; 9(4): e95246.

 

2013

Yin P#, Li Q#, Yan C, Liu Y, Liu J, Yu F, Wang Z, Long J, He J, Wang H, Wang J, Zhu J, Shi Y, Yan N*. Structural basis for the modular recognition of single-stranded RNA by PPR proteins. Nature. 2013 Dec 5; 504 (7478): 168-171.

 

2012

Lu P#, Lu G#, Yan C, Wang L, Li W and Yin P*. Structure of the mRNA splicing complex component Cwc2: insights into RNA-recognition. Biochem J. 2012 Jan 15;441(2):591-7.

 

Yin P#, Deng D#, Yan C, Pan X, Xi J, Yan N, Shi Y*. Specific DNA-RNA hybrid recognition by TAL effectors. Cell Reports. 2012 Oct 25; 2 (4):707-13.

 

Deng D#, Yin P#, Yan C, Pan X, Gong X, Qi S, Xie T, Mahfouz M, Zhu Jian-Kang, Yan N*, Shi Y*. Recognition of methylated DNA by TAL effectors. Cell Research. 2012 Oct; 22 (10):1502-4.

 

Prior to 2012

Hao Q#, Yin P#, Li W, Wang L, Yan C, Lin Z, Wu JZ, Wang J, Yan SF, Yan N*. The molecular basis of ABA-independent inhibition of PP2Cs by a subclass of PYL proteins. Mol Cell. 2011 Jun 10;42(5):662-72. 

 

Yuan X#, Yin P#, Hao Q#, Yan C, Wang J, Yan N*. Single amino acid alteration between valine and isoleucine determines the distinct pyrabactin selectivity by PYL1 and PYL2. J Biol Chem. 2010 Sep 10; 285 (37): 28953-8.

 

Hao Q#, Yin P#, Yan C#, Yuan X, Li W, Zhang Z, Liu L, Wang J, Yan N*. Functional mechanism of the abscisic acid agonist pyrabactin. J Biol Chem. 2010 Sep 10; 285 (37): 28946-52.

 

Yin P#, Fan H#, Hao Q#, Yuan X#, Wu D, Pang Y, Yan C, Li W, Wang J, Yan N*. Structural insights into the mechanism of abscisic acid signaling by PYL proteins. Nat Struct Mol Biol. 2009 Dec; 16 (12): 1230-6.

 

Yin P, Li TY, Xie MH, Jiang L, Zhang Y*. A Type Ib ParB protein involved in plasmid partitioning in a gram-positive bacterium. J Bacteriol. 2006 Dec; 188 (23): 8103-8.

 

Li TY#, Yin P#, Zhou Y, Zhang Y*, Zhang YY, Chen TA. Characterization of the replicon of a 51-kb native plasmid from the gram-positive bacterium Leifsonia xyli subsp. cynodontis. FEMS Microbiol Lett. 2004 Jul 1; 236 (1): 33-9. 2016

Others

 

Zhou L, Hang J, Zhou Y, Wan R, Lu G, Yin P, Yan C, Shi Y*. Crystal structures of the Lsm complex bound to the 3' end sequence of U6 small nuclear RNA. Nature. 2014 Feb 6;506(7486):116-20.

 

Li W, Wang L, Sheng X, Yan C, Zhou R, Hang J, Yin P, Yan N*. Molecular basis for the selective and ABA-independent inhibition of PP2CA by PYL13. Cell Research. 2013 Dec;23(12):1369-79.

 

Ma D, Lu P, Yan C, Fan C, Yin P, Wang J, Shi Y*. Structure and mechanism of a

glutamate-GABA antiporter. Nature.2012 Mar 11;483(7391):632-6.

 

Huang L, Yin P, Zhu X, Zhang Y, Ye K*. Crystal structure and centromere binding of the plasmid segregation protein ParB from pCXC100. Nucleic Acids Res. 2011 Apr 39; (7): 2954-68.

 

Bao P, Wu QJ, Yin P, Jiang Y, Wang X, Xie MH, Sun T, Huang L, Mo DD, Zhang Y*. Coordination of two sequential ester-transfer reactions: exogenous guanosine binding promotes the subsequent omegaG binding to a group I intron. Nucleic Acids Res. 2008 Dec; 36 (21): 6934-43.

 

 

Li TY, Zeng HL, Yin P, Lin H, Fan XL, Guo ZG, Zhang CF*. Construction of a stable expression vector for Leifsonia xyli subsp. cynodontis and its application in studying the effect of the bacterium as an endophytic bacterium in rice. FEMS Microbiol Lett. 2007 Feb; 267 (2):176-83.

 

Jiang YF, Xiao M, Yin P, Zhang Y*. Monovalent cations use multiple mechanisms to resolve ribozyme misfolding. RNA. 2006 Apr;12 (4): 561-6.

 

Conferences:

1) Ping Yin. Pentatricopeptide repeat proteins: the versatile tool for RNA recognition. 5th Structure Biology Symposium in China. 2016. Speaker

2) Ping Yin. Crystal structure of PPR10 with target RNA provides new insights into sequence-specific RNA recognition. 5th CSHA Symposium: Structural Biology from Atoms to Cells. 2014. Speaker

3) Ping Yin, Nieng Yan*. The Third Structure Biology Symposium in China. March 2010, Sanya, Hainan, China.

4) Ping Yin, Tai-Yuan Li* and Yi Zhang*. The First International symposium of the Protein Society. August 2006, Xiamen, Fujian, China.

 

 

 

 

主讲课程

生物化学

 

研究生招生专业

结构生物学,RNA代谢

 

联系方式

实验室电话:027-87288920

电子邮箱:yinping@mail.hzau.edu.cn

办公地点:作物遗传改良国家重点实验室(第二综合楼)A102

 

实验室介绍及网址:

http://yinlab.hzau.edu.cn

 

中国·湖北·武汉 南湖狮子山街一号430070 Tel:+86-27-87282101 Fax:+86-27-87282469
CopyRight©2001-2010 华中农业大学生命科学技术学院 版权所有; E-mail:bio@mail.hzau.edu.cn 技术支持:现代教育技术中心