发酵工程教研室Brief Introduction

彭楠
时间:2015-11-05

 

彭楠 博士  副教授  博士生导师 

教育经历

2000-2004:华中农业大学本科

2004-2006:华中农业大学硕士

2006-2009:华中农业大学博士

2008-2009:哥本哈根大学访问博士

 

科研与学术工作经历

2013.01-至今,华中农业大学,副教授;

2010.06-2012.12华中农业大学,讲师。

 

研究方向

1    CRISPR-Cas系统工作机制及其应用;

2    秸秆资源化利用(秸秆发酵生产乳酸及发酵菌株的遗传改造);

3    环境微生物对极端条件(干旱、贫瘠及高热等)的适应性机制。

 

代表性研究成果

请注意:①投稿阶段的论文不要列出;②对期刊论文:应按照论文发表时作者顺序列出全部作者姓名、论文题目、期刊名称、发表年代、卷(期)及起止页码(摘要论文请加以说明);③对会议论文:应按照论文发表时作者顺序列出全部作者姓名、论文题目、会议名称(或会议论文集名称及起止页码)、会议地址、会议时间;④应在论文作者姓名后注明第一/通讯作者情况:所有共同第一作者均加注上标“#”字样,通讯作者及共同通讯作者均加注上标“*”字样,唯一第一作者且非通讯作者无需加注;⑤所有代表性研究成果和学术奖励中本人姓名加粗显示。

论文

1.     Liu T, Liu Z, Ye Q, Pan S, Wang X, Li Y, Peng W, Liang Y, She Q, Peng N*. (2017) Coupling transcriptional activation of CRISPR-Cas system and DNA repair genes by Csa3a in Sulfolobus islandicus. Nucleic Acids Res. DOI: 10.1093/nar/gkx612. IF=10.16 (Corresponding author).

2.     Peng N, Han W, Li Y, Liang Y, She Q*. (2017) Genetic technologies for extremely thermophilic organisms of Sulfolobus genus, the only genetically tractable crenarchaea. Sci China Life Sci. 60: 1-16. IF: 2.78 (First author).

3.     Liu T, Pan S, Li Y, Peng N* She Q. (2017) Type III CRISPR-Cas system: Introduction and its application for genetic manipulations. In Book: The CRISPR/Cas System: Emerging Technology and Application. Caister Academic Press. DOI: https://doi.org/10.21775/9781910190630.01 (Corresponding author).

4.     Han W, Li Y, Deng L, Feng M, Peng W, Hallstrom S, Zhang J, Peng N, Liang Y X, White M, She Q*. (2017) A type III-B CRISPR–Cas effector complex mediating massive target DNA destruction. Nucleic Acids Res. 45(4):1983-1993. IF: 10.16

5.     Zhang Z, Xie Y, He X, Li X, Hu J, Ruan Z, Zhao S, Peng N*, Liang Y*. (2016) Comparison of high-titer lactic acid fermentation from NaOH- and NH3-H2O2-pretreated corncob by Bacillus coagulans using simultaneous saccharification and fermentation. Sci Rep. 6:37245. IF=5.22 (Co-corresponding author)

6.     Li Y, Pan S, Zhang Y, Ren M, Feng M, Peng N, Chen L, Liang Y, She Q* (2016) Harnessing Type I and Type III CRISPR-Cas systems for genome editing, Nucleic Acids Res. 29;44(4):e34. IF: 9.22

7.     Ren X, Wang J, Yu H, Peng C, Hu J, Ruan Z, Zhao S, Liang YX and Peng N*. (2016) Anaerobic and sequential aerobic production of high-titer ethanol and single cell protein from NaOH-pretreated corn stover by a genome shuffling-modified Saccharomyces cerevisiae strain. Bioresource Technol. 218: 623-630. IF: 4.91 (Corresponding author).

8.     Hu J, Lin Y, Zhang Z, Xiang T, Mei Y, Zhao S, Liang YX and Peng N*. (2016) High-titer lactic acid production by Lactobacillus pentosus FL0421 from corn stover using fed-batch simultaneous saccharification and fermentation. Bioresource Technol. 214: 74-80. IF: 5.04 (Corresponding author).

9.     Hu J, Zhang Z, Lin Y, Zhao S, Mei Y, Liang Y and Peng N*. (2015) High-titer lactic acid production from NaOH-pretreated corn stover by Bacillus coagulans LA204 using fed-batch simultaneous saccharification and fermentation under non-sterile condition. Bioresource Technol. 182: 251-257. IF: 5.04 (Corresponding author).

10.   Liu T, Li Y, Wang X, Ye Q, Li H, Liang XY, She Q and Peng N* (2015) Transcriptional regulator-mediated activation of adaptation genes triggers CRISPR de novo spacer acquisition. Nucleic Acids Res. 43 (2): 1044-1055. IF: 9.22 (Corresponding author).

11.   Wang H, Peng N, Shah S, Huang L* and She Q* (2015) Archaeal Extrachromosomal Genetic Elements. Microbiol Mol Biol Rev. 79 (1): 117-152. IF: 15.26

12.   Ao, X., Li, Y., Wang, F., Feng, M., Lin, Y., Zhao, S., Liang YX.*, and Peng, N* (2013) Sulfolobus Initiator Element is An Important Contributor to Promoter Strength. J Bacteriol, 195(22):5216-5222. IF: 3.19. (Co-corresponding author)

13.   Peng, N., Xu, WL., Wang, F., Hu, JL., Ma, MH., Hu, YL., Zhao, SM., Liang, YX., Ge, XY* (2013) Mitsuaria Chitosanase with Unrevealed Important Amino Acid Residues: Characterization and Enhanced Production in Pichia pastoris. Appl Microbiol Biotech. 97:171–179. IF: 3.81. (First author)

14.   Peng, N., Deng, L., Mei, YX., Jiang, DQ., Hu, YM., Awayez, M., Liang, YX* and She, Q* (2012) A Synthetic Arabinose-Inducible Promoter Confers High Levels of Recombinant Protein Expression in Hyperthermophilic Archaeon Sulfolobus islandicus. Appl Environ Microbiol. 78(16):5630-7. IF: 3.95 (First author).

15.   Peng, N., Ao, X., Liang, YX. and She, Q* (2011) Archaeal promoter architecture and mechanism of gene activation. Biochem Soc Trans. 2011, 39(1), 99-103. IF: 3.98 (First author).

16.   Peng, N., Xia, Q., Chen, ZJ., Liang, YX. and She, Q* (2009). An upstream activation element exerting differential transcriptional activation on an archaeal promoter. Mol Microbiol. 2009, 74 (4), 928-939. IF: 5.36 (First author).

 

授权专利

1.     梁运祥张东晓;赵述淼葛向阳;彭楠王绩陈路一种毕赤酵母培养基重复发酵利用的方法2011. 公开号:CN102242153A

2.     梁运祥,涂飞,赵述淼,葛向阳,彭楠,王绩,王玢. 固态发酵生产冬虫夏草菌丝的方法. 20130605(专利号:ZL201110116928.2

 

基金项目

1.     国家自然科学基金面上项目(3167080536):嗜热古菌I-ACRISPR-Cas系统原发适应的分子机制,2017.01-2020.12,主持。

2.     公益性行业(农业)科研专项(201503137),作物秸秆基质化利用子课题:秸秆发酵生产乳酸综合工艺的开发,2015.01-2019.12,主持。

3.     国家自然科学基金青年科学基金项目(31100050):极端嗜热古菌阿拉伯糖启动子转录激活模式的研究,2012.01-2014.12,主持。

4.     武汉东湖高新区第六批(2013“3551光谷人才计划新型绿色有机壳寡糖生物农药的开发及产业化应用,主持。

5.     中央高校基本科研业务(2011QC025, 2662015PY038, 2662015PX199, 2662016PY129),主持。

 

获得奖励

20122016年获华中农业大学教学质量三等奖

 

主讲课程

分子生物学,氨基酸发酵工艺技术,现代生物工程与技术实验

 

研究生招生专业

微生物学

 

联系方式

实验室电话:027-87281267

电子邮箱:nanp@mail.hzau.edu.cn

办公地点:农业微生物学国家重点实验室A414

 

实验室介绍及网址:

 

中国·湖北·武汉 南湖狮子山街一号430070 Tel:+86-27-87282101 Fax:+86-27-87282469
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