Research Interest:
Synthetic biology, metabolic engineering
Education:
Ph. D in Biochemistry and Molecular Biology
2007-2014: Chungnam National University, Daejeon, Korea(S)
B.A. in Biotechnology
2003-2007: Shenzhen University, Shenzhen, Guangdong province, China
Professional Experiences:
Mar 2015- Aug 2018, Huazhong Agricultural University, Hubei province, China
Associate Professor
Sep 2018- Until now, Huazhong Agricultural University, Hubei province, China
Selected Publications:
1. Wang X, Abishek NMP, Jeon HJ, Lee Y, He J, Adhya S, Lim HM. (2019) Processing generates 3’ ends of RNA masking transcription termination events in prokaryotes. P Natl Acad Sci USA 116 (10): 4440-4445.
2. Wang X, Cai X, Ma HD, Yin W, Zhu L, Li XF, Lim HM, Chou SH, He J. (2019) A c-di-AMP riboswitch controlling kdpFABC operon transcription regulates the potassium transporter system in Bacillus thuringiensis. Commun Biol 2 (1): 151.
3. Wang X, Jeon HJ, Abishek NMP, He J, Lim HM. (2018) Visualization of RNA 3’ ends in Escherichia coli using 3’ RACE combined with primer extension. Bio-protocol 8 (5) e2752
4. Wang X, Z. Li, X. Li, H.L. Qian, X. Cai, X.F. Li & J. He, (2016) Poly-beta-hydroxybutyrate metabolism is unrelated to the sporulation and parasporal crystal protein formation in Bacillus thuringiensis. Front Microbiol 7:836.
5. Wang X, Ji SC, Lim HM. (2015) Two-level inhibition of galK expression by Spot 42: Degradation of mRNA mK2 and enhanced transcription termination before the galK gene. P Natl Acad Sci USA 112 (24): 7581-7586.
6. Wang X, Ji SC, Yun SH, Jeon HJ, Kim SW, Lim HM. (2014). Expression of each cistron in the gal operon can be regulated by transcription termination and generation of a galK-Specific mRNA, mK2. J Bacteriol 196 (14): 2598-2606.
7. Ji, SC, Wang X, Yun, SH, Jeon, HJ, Lee HJ, Lim, HM. (2011) In vivo transcription dynamics of the galactose operon: a study on the promoter transition from P1 to P2 at onset of stationary phase. PLoS ONE, 6(3): e17646.
8. Ji, SC, Wang X, Jeon, HJ, Yun, SH, Lee, HJ, Lim, HM. (2010) Quantification of the galactose-operon mRNAs 5 bases different in their 5'-ends. BMB Rep, 43 (7): 474-479.
9. Zheng C, Ma Y, Wang X, Xie Y, Ali MK and He J. (2015) Functional analysis of the sporulation-specific diadenylate cyclase CdaS in Bacillus thuringiensis. Front Microbiol 6: 908.
10. Zhang S, Hu Y, Fan Q, Wang X, He J. (2015) Two-component system YvqEC-dependent bacterial resistance against vancomycin in Bacillus thuringiensis. Antonie van Leeuwenhoek. 108 (2): 365-376.
11. Zhang SM, Li XF, Wang X, Li Z, He J. (2016) The two-component signal transduction system YvcPQ regulates the bacterial resistance to bacitracin in Bacillus thuringiensis. Archives of Microbiology, 198: 773-784.
12. Yun, SH, Ji, SC, Jeon, HJ, Wang X, Kim, SW, Bak, G., Lee, Y, Lim, HM. (2012) The CnuK9E H-NS complex antagonizes DNA binding of DicA and Leads to temperature-dependent filamentous growth in E. coli. PLoS ONE, 7(9): e45236.
13. Yun, SH, Ji, SC, Jeon, HJ, Wang X, Lee, Y, Choi, BS, Lim, HM. (2012) A mutational study of Cnu reveals attractive forces between Cnu and H-NS. Mol Cells. 33(2): 211-216.
