赖志兵 博士、教授、博士生导师,入选省部级重要青年人才项目
教育经历:
2006.01-2010.06 普渡大学(美国),植物和植物病理学系,博士学位
1999.09-2002.12 南京农业大学,植物病理学系,硕士学位
1995.09-1999.07 江西农业大学,植物保护系,学士学位
科研与学术工作经历:
2013.11-至今 华中农业大学生命科学技术学院教授/作物遗传改良国家重点实验室独立PI
2010.06-2013.11 普渡大学(美国),博士后
研究方向:
本课题组以玉米和模式植物为研究对象,结合遗传学、生物化学和多种组学技术,克隆植物抗病基因、揭示植物-病原菌互作分子机制,为作物遗传改良提供新的抗病材料、新的抗病基因和新的育种思路。研究方向包括
1. 玉米抗病基因克隆和抗病分子机制解析;
2. 玉米-病原真菌互作分子机制解析;
3. 细胞自噬介导的植物抗病分子机制解析;
科研项目
1. 国家自然基金面上项目,玉米抗灰斑病qRglsSB基因的克隆及其抗病分子机理的研究,项目批准号:32072007;在研;
2. 国家自然基金国际(地区)合作与交流项目(组织间合作研究-NSFC-CGIAR项目I(国际组织)),玉米抗大斑病遗传基础的剖析和利用,项目批准号:31761143008;在研;
3. 国家重点研发计划(2016YFD0101002)小麦等作物功能基因组研究与应用;子课题,玉米模拟病斑抗性QTL的克隆及抗病调控网络的探索,2016.07.01-2021.06-30,结题;
4. 国家自然基金面上项目,抗玉米南方锈病基因RppK22的克隆及其抗病分子机理的研究,项目批准号:31571676;结题;
代表性研究成果:(*通讯作者,#共同第一作者)
1. Chen, G., Zhang, B., Ding, J., Wang, H., Deng, C., Wang, J., Yang, Q., Pi, Q., Zhang, R., Zhai, H., Dong, J., Huang, J., Hou, J., Wu, J., Que, J., Zhang, F., Li, W., Min, H., Tabor, G., Li, B., Liu, X., Zhao, J., Yan, J.*, and Lai, Z*. (2022) Cloning southern corn rust resistant gene RppK and its cognate gene AvrRppK from Puccinia polysora. Nat Communications. 13:4392. (*通讯作者) (IF: 14.919)
2. Wang, H., Hou, J., Ye, P., Hu, L., Huang, J., Dai, Z., Zhang, B., Dai, S., Que, J., Min, H., Chen, G., Wang, Y., Jiang, M., Liang, Y., Li, L., Zhang, X., Lai, Z*. (2021) A Teosinte-derived Allele of a MYB Transcription Repressor Confers Multiple Disease Resistance in Maize. Molecular Plant. 14:1846-1863. (*通讯作者) (IF: 13.164)
3. Zhang, B., Shao, L., Wang, J., Zhang, Y., Guo, X., Peng, Y., Cao, Y., Lai, Z*. (2021) Phosphorylation of ATG18a by BAK1 suppresses autophagy and attenuates plant resistance against necrotrophic pathogens. Autophagy. 17(9): 2093-2110. (*通讯作者) (IF: 16.016)
4. Zhang, Y., Zhang, Y., Yu, D., Peng, Y., Min, H., Lai, Z*. (2020) Copper ions are required for Cochliobolus heterostrophus in appressorium formation and virulence on maize. Phytopathology. 110(2): 494-505. (*通讯作者) (IF: 4.025)
5. Li, G., Wang, J., Li, D., Liu, S., Yin, J. *, Lai, Z. *, Yang, G*. A Hg(II)-specific probe for imaging application in living systems and quantitative analysis in environmental/food samples. Chinese Chemical Letters. DOI: 10.1016/j.cclet.2020.09.040. (*通讯作者) (IF: 4.632)
6. Liao, C., Lai, Z., Lee, S., Yun, D., Mengiste, M*. (2016) Arabidopsis HOOKLESS1 regulates responses to pathogens and abscisic acid through interaction with MED18 and acetylation of WRKY33 and ABI5 chromatin. Plant Cell. 28(7): 1662-1681. (IF: 9.61)
7. Lai, Z., Schluttenhoffer, S.M., Bhide, K., Jacob, S., Thimmapuram, J., Lee, S.Y., Yun, DJ., Mengiste T*. (2014) MED18 interacts with distinct transcription factors regulates plant immunity, flowering time and responses to hormones. Nature Communications. 5:3064. (IF: 12.12)
8. Lai, Z., Mengist, T*. (2013) Genetic and cellular mechanisms regulating plant responses to necrotrophic pathogens. Current opinion in plant biology.16: 505-512.
9. Lai, Z., Li, Y., Wang, F., Cheng, Y., Fan, B., Yu, J., and Chen, Z*. (2011) Arabidopsis Sigma Factor-Binding Proteins are Activators of WRKY33 Transcription factor in Plant Defense. Plant Cell. 23: 3824-3841.
10. Laluk, K., Luo, H., Chai, M., Dhawan, R., Lai, Z., Mengiste, T*. (2011) Biochemical and Genetic Requirements for Function of the Immune Response Regulator BOTRYTIS-INDUCED KINASE1 in plant growth, Ethylene Signaling, and PAMP-Triggered Immunity in Arabidopsis. Plant Cell. 23: 2831-2849.
11. Lai, Z., Wang, F., Zheng, Z., Fan, B., Chen, Z*. (2011) A Critical Role of Autophagy in Plant Resistance to Necrotrophic Fungal Pathogens. Plant Journal. 66: 953-968.
12. Ellwood, SR., Liu, Z., Syme, RA., Lai, Z., Hane, JK., Keiper, F., Moffat, CS., Oliver, RP., Friesen, TL*. (2010) A first genome assembly of the barley fungal pathogen Pyrenophora teres f. teres. Genome Biol. 11(11): R109.
13. Luo, H., Laluk, K., Lai, Z., Veronese, P., Song, F., and Mengiste, T*. (2010) The Arabidopsis Botrytis Susceptible 1 interactor defines a subclass of RING E3 ligases that regulate pathogen and stress responses. Plant Physiology. 154: 1766-1782.
14. Huang, J., Gu, M., Lai, Z., Fan, B., Shi, K., Zhou, YH., Yu, JQ., Chen, Z*. (2010) Functional analysis of the Arabidopsis PAL gene family in pant growth, development, and response to environmental stress. Plant Physiology. 153: 1526-1538.
15. Chen, H., Lai, Z., Shi, J.-W., Xiao, Y., Chen, Z., and Xu, X*. (2010) Roles of Arabidopsis WRKY18, WRKY40 and WRKY60 transcription factors in plant responses to abscisic acid and abiotic stress. BMC Plant Biology 10: 281.
16. Chen, Z.*, Zheng, Z., Huang, J., Lai, Z. and Fan, B. (2009) Biosynthesis of salicylic acid in plants. Plant Signaling & Behavior 4:6, 493-496.
17. Kim, K., Lai, Z., Fan, B., and Chen, Z*. (2008) Arabidopsis WRKY38 and WRKY62 function partially redundantly as negative regulators of systemic acquired resistance. Plant Cell 20:2357-2371.
18. Lai, Z., K. M. Vinod., Zheng, Z., Fan, B., and Chen, Z*. (2008) Role of Arabidopsis WRKY3 and WRKY4 transcription factors in plant responses to pathogens. BMC Plant Biology 8:68.
19. Xing D.#, Lai, Z.#, Zheng, Z., Fan, B., and Chen, Z*. (2008) Stress- and pathogen-induced Arabidopsis WRKY48 is a transcriptional activator that represses plant basal defense. Mol. Plant 1:459-470. (# co-first author)
20. Lai, Z., Faris, J. D., Weiland, J. J., Steffenson, B. J., and Friesen, T. L*. (2007) Genetic mapping of Pyrenophora teres f. teres genes conferring avirulence on barley. Fungal Genet Bio. 44: 323-329.
21. Friesen, T. L.*, Faris, J. D., Lai, Z., and Steffenson, B. J. (2006) Identification and chromosomal location of major genes for resistance to Pyrenophora teres f. teres and P. teres f. maculata in a barley doubled haploid population. Genome 49:855-859.
主讲课程:
普通生物学
研究生招生专业:
遗传学,生物化学和分子生物学;
联系方式:
电子邮箱:zhibing@mail.hzau.edu.cn
办公地点:作物遗传改良国家重点实验室(第二综合楼)B210