Cinque Terre

赵毓

来源: 责任编辑: 发布:2015-11-03 点击量:


 

 

赵毓   博士   教授   博士生导师   教育部新世纪人才计划入选者

 

教育经历

1992-1996 汉中师范学院 生物系 生物教育专业 教育学学士学位

1997-2000 西北农林科技大学  生命科学学院  植物学专业  理学硕士

2004-2009 华中农业大学 生命科学技术学院 生物化学与分子生物学专业 理学博士学位

 

科研与学术工作经历

2017-至今 华中农业大学 生命科学技术学院 教授

2016.03-2016.10 巴黎十一大学 萨克雷植物研究所 高级访问学者

2009-2016 华中农业大学 生命科学技术学院 讲师,副教授

 

研究方向

从植物器官发生、调控等科学问题出发,对研究水稻冠根(不定根)产生的遗传和表观遗传机制进行研究。

 

代表性研究成果

研究论文

1. Lu Y, Zhou DX, Zhao Y* (2020). Understanding epigenomics based on the rice model. Theor Appl Genet. 133(5):1345-1363.

2. Hu Y,* Lai Y, Chen X, Zhou DX, Zhao Y*(2020). Distribution pattern of histone marks potentially determines their roles in transcription and RNA processing in rice. J. Plant Physiol., 249:153167

3. Lu Y, Tan F, Zhao Y, Chen X, Zhou S, Hu Y, Zhou DX. A Chromodomain-Helicase-DNA-like Binding Factor Functions in Chromatin Modification and Gene Regulation. Plant Physiology. 2020 183(3):1035-1046

4. Huang H, Ullah F, Zhou DX, Yi M, Zhao Y*(2019). Mechanisms of ROS Regulation of Plant Development and Stress Responses. Front Plant Sci., 10:800

5. Hu Y, Lu Y, Zhao Y, Zhou DX (2019). Histone Acetylation Dynamics Intergrates Metabolic Activity to regulate plant response to stress. FRONT PLANT SCI, 10:123

6. Zhou S, Jiang W, Zhao Y, Zhou DX. (2019). Single-cell three-dimensional genome structures of rice gametes and unicellular zygotes. Nat Plants. 2019. 5(8):795-800.

7. Cheng S, Tan F, Lu Y, Liu X, Li T, Yuan W, Zhao Y*, Zhou DX*(2018). WOX11 recruits a histone H3K27me3 demethylase to promote gene expression during shoot development in rice. Nucleic Acids Res., 46(5):2356-2369 (co- correspondence)

8. Lu Y, Xu Q, Liu Y, Yu Y, Cheng ZY, Zhao Y, Zhou D-X*(2018): Dynamics and functional interplay of histone lysine butyrylation, crotonylation, and acetylation in rice under starvation and submergence. Genome Biol., 19:144.

9. Tan F, Lu Y, Jiang W, Wu T, Zhang R, Zhao Y, Zhou D-X*(2018): DDM1 Represses Noncoding RNA Expression and RNA-Directed DNA Methylation in Heterochromatin. Plant Physiology, 177:1187-1197.

10. Zhou C, Wang C, Liu H, Zhou Q, Liu Q, Guo Y, Peng T, Song J, Zhang J, Chen L, Zhao Y, Zeng Z*, Zhou D-X*(2018): Identification and analysis of adenine N(6)-methylation sites in the rice genome. Nature Plants 2018, 4:554-563.

11. Zhang H, Zhao Y, Zhou D-X*(2017): Rice NAD+-dependent histone deacetylase OsSRT1 represses glycolysis and regulates the moonlighting function of GAPDH as a transcriptional activator of glycolytic genes. Nucleic Acids Res., 45:12241-12255

12. Zhou S, Jiang W, Long F, Cheng S, Yang W, Zhao Y*, Zhou DX*(2017). Rice homeodomain protein WOX11 recruits a histone acetyltransferase complex to establish programs of cell proliferation of crown root meristem. Plant Cell, 29(5):1088-1104 (co- correspondence)

13. Jiang W, Zhou S, Zhang Q, Song H, Zhou DX, Zhao Y* (2017). Transcriptional regulatory network of WOX11 involved in the control of crown root development, cytokinin signals, and redox in rice. J. Exp. Bot., 68(11):2787-2798

14. Cheng S, Zhou D-X, Zhao Y* (2016). WUSCHEL-related homeobox gene WOX11 increases rice drought resistance by controlling root hair formation and root system development. Plant SignalBehavior, 11(2):e1130198

15. Tan F, Zhou C, Zhou Q, Zhou S, Yang W, Zhao Y, Li G, Zhou D-X* (2016). Analysis of DDM1 and DRM2 orthologs reveals specific features of rice DNA methylation pathways. Plant Physiol 171(3):2041-54

16. Zhou S, Liu X, Zhou C, Zhou Q, Zhao Y, Li G, Zhou D-X* (2016). Cooperation between the H3K27me3 chromatin marker and non-CG methylation in epigenetic regulation. Plant Physio, 172(2):1131-1141

17. Zhang H, Lu Y, Zhao Y, Zhou Dao-Xiu (2016). OsSRT1 is involved in rice seed development through regulation of starch metabolism gene expression. Plant Science. 248:28-36

18. Zhao Y*, Cheng S, Song Y, Huang Y, Zhou S, Liu X, Zhou D-X (2015). The interaction between rice ERF3 and WOX11 promotes crown root development by regulating gene expression involved in cytokinin signaling. Plant Cell, 27(9)2469-83

19. Li J, Zhao Y*, Chu H, Wang L, Fu Y, Liu P, Upadhyaya N, Chen C, Mou T, Feng Y, Kumar P, and Xu J* (2015). SHOEBOX modulates root meristem size in rice through dose-dependent effects of gibberellins on cell elongation and proliferation PLoS Genetics, 11(8):e 1005464

20. Chen X, Liu X, Zhao Y, Zhou D-X* (2015). Histone H3K4me3 and H3K27ME3 regulatory genes control stable transmission of an epimutayion in rice. Sciencific Report, 5:13251.

21. Liu X, Zhou S, Wang W, Ye Y, Zhao Y, Xu Q, Zhou C, Tan F, Cheng S, and Zhou D-X* (2015) Regulation of Histone Methylation and Reprogramming of Gene Expression in the Rice Inflorescence Meristem. Plant Cell, 27(5): 4725–4736

22. Zhu N, Cheng S, Liu X, Du H, Dai M, Zhou D-X, Yang W, Zhao Y* (2015). The R2R3-type MYB gene OsMYB91 has a function in coordinating plant growth and salt stress tolerance in rice. Plant Science, 236146–156

23. Zhang J, Tang W, Huang Y, Niu X, Zhao Y, Han Yi*, Liu Y* (2015). Down-regulation of a LBD-like gene, OsIG1, leads to occurrence of unusual double ovule and developmental abnormalities of various floral organs and megagametophyte in rice. J. Exp. Bot., 66(1):99-112.

24. Cheng S, Huang Y, Zhu N, Zhao Y* (2014). The rice WUSCHEL-related homeobox genes are involved in reproductive organ development, hormone signaling and abiotic stress response. Gene, 266-274.

25. Liu X, Zhou C, Zhao Y, Zhou S, Wang W and Zhou D-X*(2014). The rice enhancer of zeste[E(z)] genes SDG711 and SDG718 are respectively involved in long day and short day signaling to mediate the accurate photoperiod control of flowering time. Frontiers in Plant Science, 5:591

26. Li T, Chen X, Zhong X, Zhao Y, Liu X, Zhou S, Cheng S, Zhou D-X* (2013). Histone demethylase JMJ705-mediated remove of histone H3 lysine 27 trimethylation is involved in defense-related gene activation in rice.

27. Plant Cell. 25: 4725–4736

28. Zhong X, Zhang H, Zhao Y, Sun Q, Hu Y, Peng H, Zhou D-X* (2013). The rice NAD+-dependent histone deacetylase OsSRT1 targets preferentially to stress and metabolism-related genes and transposable elements. PLoS ONE. 8(6):e66807

29. Hu Y, Zhu N, Wang X, Yi Q, Zhu D, Lai Y, Zhao Y* (2013)Analysis of rice Snf2 family proteins and their potential roles in epigenetic regulation. Plant Physiology and Biochemistry. 70C:33-42

30. Zhao YZhou D-X*2012Epigenomic modification and epigenetic regulation in rice. J. Gen. Genomics. 39(7): 307-315

31. Wu J, Du H, Liao X, Zhao Y, Li L, Yang L* (2011). Tn5 transposase-assisted transformation of indica rice. Plant J. 68,186-200

32. Wu J, Du H, Liao X, Zhao Y, Li L, Yang L* (2011). An improved particle bombardment for the generation of transgenic plants by direct immobilization of relleasable Tn5 transposases onto gold particles. Plant Mol Biol. 77:117–127

33. Li C, Huang L, Xu C, Zhao Y, Zhou D-X * (2010). Altered levels of histone deacetylase OsHDT1 affect differential gene expression patterns in hybrid rice. PLoS ONE. 6(7): e21789

34. Zhao Y, Hu Y, Dai M, Huang L, Zhou D-X*(2009). The Wuschel-related homoeobox gene WOX11 is required to activate shoot-borne crown root development in rice. Plant Cell. Vol.21:736-748

35. Hu YQin F, Huang L, Sun Q, Li C, Zhao Y, Zhou D-X*2009. Rice histone deacetylase genes display specific expression patterns and developmental functions. Biochem Biophys Res Commun 388: 266–271

36. Xue W, Xing Y, Weng X, Zhao Y, Tang W, Wang L, Zhou H, Yu S, Li X, Zhang Q*(2008). Natural variation in Ghd7 is an important regulator of heading date and yield potential in riceNature Genetics 40:761-767

37. Dai M, Hu Yg, Ma Q, Zhao Y, Zhou D-X*(2008). Functional analysis of rice HOMEOBOX4 (Oshox4) gene reveals a negative function in gibberellin responses. Plant Mol. Biol., 66:289-301.

38. Dai M, Zhao Y, Ma Q, Hu Y, Hedden P, Zhang Q, Zhou D-X*(2007). The rice YAB1 gene is involved in the feedback regulation of gibberellin metabolism. Plant Physiol., 144:380-390.

39. Dai M, Hu Y, Zhao Y, Liu H, Zhou D-X*(2007). Rice WUSCHEL-LIKE HOMEOBOX3 (WOX3) represses YABBY3 (YAB3) expression required for shoot development. Plant Physiol., 144:121-133.

40. Dai M, Hu Y, Zhao Y, Zhou D-X*(2007). Regulatory Networks Involving YABBY Genes in Rice Shoot Development. Plant Signaling & Behavior. 5:399-400.

41. Huang L, Sun Q, Qin F, Li C, Zhao Y, Zhou D-X*(2007). Down-regulation of a silent information regulator2-related gene, OsSRT2 induces DNA fragmentation and cell death in rice. Plant Physiol., 144:1508-1519.



授权专利

1.  E3泛素连接酶基因OsPIW调控水稻根的功能及应用授权号:ZL201510132891.0, 发明人:赵毓,蒋玮,黄玉兰,周道绣;授权日:2018.04.24

2.  一种乙烯应答因子基因OsERF3及其启动子在调控水稻根发育中的用途,授权号:ZL201210224636.5, 发明人:赵毓,程赛凤,周道绣;授权日:2016.05.30

3.  OsMYB91转录因子基因在水稻发育和抗逆中的应用 专利授权号:ZL201310086357.1 发明人:赵毓,朱宁,周道绣;授权日:2015.01.22

4.  发明名称:组蛋白去乙酰化酶基因在调控水稻种子淀粉发育中的应用,授权号:ZL201310484348.8  发明人:周道绣;张华;赵毓  授权日:2015.04.22

5.  发明名称:组蛋白甲基转移酶SDG723在调控水稻抽穗期中的应用,授权号:ZL201310454162.8  发明人:周道绣;张华;赵毓;授权日:2015.10.21

6.  发明名称:组蛋白甲基转移酶基因在调控水稻开花期和穗形中的应用, 授权号:ZL201310079799.3  发明人:周道绣;刘小云;赵毓; 授权日:2013.03.13

7.  发明名称:一个调控水稻根生长发育的转录因子基因OsWOX20的克隆及应用 专利授权号:ZL200710052664.2; 发明人:赵毓,周道绣;授权日:2011.08.09

8.  美国专利:Cloning Transcription Factor Gene OsWOX20 That Regulates The Growth and Development of Monocotyledon's Root and Uses Thereof.United States Application US20110160444 2011.06.30

 

其他成果

1.  参编《植物学实验指导》(第3版),2017年 高等教育出版社

2.  参编教学辅助材料《狮山兰芷》,2014年 科学出版社

3.  参写《Genetics and Genomics of Rice》中的第9Epigenomics,2013年由Springer集团出版。

 

获得奖励:

2018年获华中农业大学教学质量优秀奖一等奖

2017年华中农业大学植物生物学庐山实习优秀指导教师

2016年第十六届湖北省自然科学优秀学术论文二等奖(排名第一)

2015年获得湖北省细胞生物学会第三届“优秀青年学者”奖

2014年获华中农业大学教学质量优秀奖二等奖

2012年和2013年指导的园林专业和农学专业的本科生分别获得湖北省植物学实验技能大赛三等奖

2012年入选教育部新世纪优秀人才计划

2012年指导本科生获得湖北省优秀学士学位论文

2012年获得湖北省优秀学士学位论文指导教师

2010年湖北省自然科学优秀学术论文一等奖(排名第一)

2010年被华中农业大学共青团委评为第七届“十大青年岗位能手”

20062007年分别获华中农业大学教学质量优秀奖三等奖和青年教师讲课竞赛三等奖

2004年被评选为华中农业大学大学生科技创新优秀指导老师

20012002年分别获华中农业大学教学质量优秀奖二等奖

 

主讲课程

本科生课程:发育生物学、植物生物学、植物生物学实验、植物学、植物学实验、植物学野外实习、植物学基础

研究生课程:植物显微技术、高等植物学专题

植物学慕课

https://www.icourse163.org/home.htm?userId=1019682851#/home/course

 

研究生招生专业

发育生物学、细胞生物学和表观遗传学

 

联系方式

实验室电话:027-87281800

电子邮箱:zhaoyu@mail.hzau.edu.cn

办公地点:作物遗传改良国家重点实验室(第二综合楼)B512

 

实验室介绍及网址:

水稻课题组表观调控实验室

http://ibi.hzau.edu.cn/clstest/researchers.php?id=255

 

 


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